Chronic Obstructive Lung Disease
DescriptionAn in-depth report on the causes, diagnosis, treatment, and prevention of COPD -- emphysema and/or chronic bronchitis.
Alternative NamesAlpha-1 Antitrypsin Deficiency; Bronchitis: Chronic; Chronic Bronchitis; Chronic Obstructive Pulmonary Disease; Emphysema
Quitting Smoking and Avoiding Other Irritants
Quitting smoking is the first and most essential step in treating chronic obstructive lung disease and slowing its progress. In many people who quit, lung function stabilizes and eventually declines at about the rate of nonsmokers in the same age group. In some people, lung function may even improve slightly after quitting. A number of effective aids, including nicotine replacement devices and antidepressants such as bupropion (Zyban), are available that are proving to help people quit. [For more information, see Well-Connected Report #41, Smoking.]
Preventing Upper Respiratory Infections
Good Hygiene. Everyone should wash his or her hands before eating and after going outside. Ordinary soap is sufficient. Antibacterial soaps add little protection, particularly against viruses. In fact, one study suggests that common liquid dish washing soaps are up to 100 times more effective than antibacterial soaps in killing respiratory syncytial virus (RSV), which is known to cause pneumonia.
Vaccines. There are two important vaccinations to help protect against respiratory infection.
[For more information, see Well-Connected Report #94, Colds and Flus.]
Pursed-Lip Breathing. A technique called pursed-lip breathing can help improve lung function before starting activities. It takes about 10 minutes. When first learning the technique, the patient should lie flat on a bed with his or her head on a pillow. Later, the technique can be performed while walking or enduring any activity requiring extra air.
Breath Holding and Coughing. A simple technique is to inhale deeply and slowly, holding the breath for five to 10 seconds. Then the patient coughs on exhalation.
Fluids and Humidity. Patients who experience congestion and heavy sputum can benefit from maintaining good fluid intake and keeping their homes humidified.
Expectorants. Although unproven, many patients report benefits from using over-the-counter expectorant drugs that thin mucus. These drugs should not be used during an acute acerbation of COLD, however.
Chest Therapy. Chest therapy involves rhythmic inhalation for three or four deep breaths followed by coughing to produce sputum. Tapping the chest may also help in loosening and raising sputum. This should be avoided during an acute exacerbation of COLD.
Postural Drainage. The patients should also practice postural drainage. This involves leaning over the side of the bed, head down with elbows on a pillow placed on the floor. A family member or caregiver thumps gently on the back while the patient coughs.
Mucus-Producing Coughs. When coughing to produce mucus, one effective method is to lean forward and "huff" repeatedly, take relaxed breaths, and huff again. If possible, forceful coughing should be avoided.
Devices for Improving Lung Function
Flutter Valve. The flutter valve is a small hand-held device that looks like a pipe. It contains a steel ball that sits in a small plastic cone. The patient inhales deeply, holding the breath for two to three seconds. As the patient exhales (keeping the cheeks in), the ball is pushed up toward the top of the device and then falls back down. About 10 to 50 vibrations per second are generated and transmitted to the lungs to help loosen secretions. This is repeated for up to 15 breath cycles. The patient coughs at the end.
Chest Compression Devices. Devices are available that allow the patient to be passive and still expel air. One called the Vest (formerly the ThAIRapy Vest) consists of an inflatable vest attached by hoses to a generator that triggers pulses of air into the vest. The rapid pressure and release of the air around the chest acts like tiny hugs to create small coughs. It is very expensive, (about $16,000) but may be covered by insurance for specific patients.
Neuromuscular Electrical Stimulation (NMES). An investigative device uses electrical pulses to stimulate muscles in the legs. In an early study, patients were treated for 16 minutes per leg during the first week and 30 minutes per leg thereafter for a total of 30 sessions. At the end of six weeks, endurance capacity increased significantly and patients reported less muscle fatigue and shortness of breath.
Certain physical exercise may be very helpful.
Strengthening Exercises for the Limbs. Exercising and strengthening the limb muscles helps some patients improve their endurance and reducing breathlessness.
Walking. In studies of lung rehabilitation, regular exercise increases walking distance and improves breathing. Walking is the best exercise for people with emphysema. Patients should try to walk three to four times daily for five to 15 minutes each time. Devices that assist ventilation may reduce breathlessness that occurs during exercise.
Yoga and Eastern Practices. Yoga or tai chi practices, which use deep breathing and medication techniques, may be particularly beneficial for COPD patients. A clinical trial is underway to determine if yoga is helpful for COPD patients.
Inspiratory Muscle Training and Incentive Spirometer. Inspiratory muscle training involves exercises and devices that make inhaling more difficult in order to strengthen breathing muscles. In a 2001 study, patients who took part in a training group improved their breathing, walking capacity, and quality of life. The use of an incentive spirometer for 15 minutes twice a day may also be helpful as part of a training program. It also helps loosen sputum. This is a small hand-held device that contains a breathing gauge. The patient exhales and then inhales forcefully through the tube, using the pressure of the inhalation to raise the gauge to the highest level possible. A device called a peak inspiratory flow (PIF) meter measures the patients ability to draw air into the lungs and assesses the fitness of the breathing muscles.
Protein and Fats. Many COLD patients are deficient in protein. Although most healthy diets emphasize proteins from fish, poultry, and lean meat, people with COLD may benefit from foods with a higher fat content than average. (People should still prefer healthy fats, however, such as those found in olive oil and oily fish.) Some evidence suggests that high-carbohydrate meals may reduce exercise capacity.
Fruits,Vegetables, and Whole Grains. Healthy foods are important for lung function as they are for health in general. Specific foods that may be important for healthy lungs are those that contain antioxidants (best obtained from fresh, deep green and yellow-orange fruits and vegetables}, selenium (fish, red meat, grains, eggs, chicken, liver, garlic), plant chemicals called flavonoids (apples, onions), and magnesium (green leafy vegetables, nuts, whole grains, milk, and meats). It should be noted, however, that studies on general eating habits rarely provide hard evidence.
Fish Oil. Omega-3 fatty acids, found in cold water oily fish and in supplements (preferably DHA-EPA, which are the important compounds in fish oil) have anti-inflammatory effects. Some weak evidence suggests that fish oil may be helpful for people with COLD.
Alcohol and Red Wine. Some evidence suggests that resveratrol (a chemical found in red wine, grapes, olive oil) may have various health benefits, including possible protection of the lungs. In people who are not at risk for abuse, moderate intake of wine may be healthful, although there is no evidence that wine itself improves lung function, and high amounts can impair the immune system. Women who are pregnant or at high risk for breast cancer, people who can't drink moderately, and people with liver disease should avoid alcohol.
Dietary Supplements. Some studies report benefits for COLD patients who took supplements of N-acetyl-cysteine, a powerful antioxidant that is a form of cysteine-a common amino acid in the body. Other antioxidants being studies include L-carnitine and coenzyme Q10. Evidence of benefit is weak, however, for all these chemicals.
No vitamin or mineral supplements have been proven to improve lung function. The trace elements zinc and selenium may have some effect in reducing the severity of upper respiratory tract infections, but they should be obtained in food. One study found protection from diets rich in vitamin C, but other specific antioxidants, including vitamins E, A, and beta carotene, had no effect. Furthermore, there is some evidence exists that high doses of anti-oxidant vitamin supplements can be harmful. In fact, a surprising study in 2002 reported a higher incidence and greater severity of respiratory infections in older adults who took 200 mg of vitamin E daily. Beta carotene supplements, in any case, are not recommended because of studies suggesting an increased risk of lung cancer in smokers.
Patients with COLD have a high risk for depression and anxiety, which can impair outlook. Psychologic and social supports are important for improving emotional states, for coping with daily stresses, and maintaining independence and social relationships. Patients who have emotional difficulties should consider group support or individual counseling.
Minimizing Airborne Contaminants
As much as possible, a patient should avoid exposure to airborne irritants, including hair sprays, aerosol products, paint sprayers, and insecticides.
To minimize the amount of contaminants in the home, the following may be helpful measures: