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ENCYCLOPEDIA INDEX

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CPK isoenzymes

Alternative Names:

Creatine phosphokinase - isoenzymes; Creatine kinase - isoenzymes; CK - isoenzymes

What abnormal results mean:

Higher-than-normal CPK-1 levels may occur with the following:

Higher-than-normal CPK-2 levels may occur with the following:

Heart attack
- There is a significant rise in CPK-2 levels in the first 2 to 3 hours after a heart attack. This test is used to diagnose a heart attack.
- The extent of the elevation depends on the severity of the heart attack. CPK levels may remain elevated up to 24 hours after a heart attack, and sometimes even longer.
Myocarditis (inflammation of the heart muscle usually due to a virus)
Electrical injuries
Trauma to the heart (for instance, from a car accident)
Heart defibrillation (purposeful shocking of the heart by medical personnel)
Open heart surgery

Higher-than-normal CPK-3 levels may occur with the following:

Crush injuries of skeletal muscle
Multiple intramuscular injections
Muscular dystrophy
Myositis (skeletal muscle inflammation)
Post-electromyography (a test of nerve and muscle function)
Recent seizures
Recent surgery
Rhabdomyolysis (skeletal muscle damage due to drugs or prolonged immobilization)
Strenuous exercise