1. Health

, former

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

ENCYCLOPEDIA INDEX
Injury Disease Nutrition Poison Symptoms Surgery Test Special Topic
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Malignant hyperthermia

Overview Symptoms Treatment Prevention
Alternative Names:
Hyperthermia - malignant; Hyperpyrexia - malignant
Treatment:
The best course of action for this condition is prevention. If a general anesthetic is to be given, pretreatment with dantrolene sodium is recommended. If you have a family history of anesthesia-induced problems it is imperative to alert your surgeon and anesthesiologist.

For an episode of malignant hyperthermia, antipyretics (fever-reducing medications such as acetaminophen) and a cooling blanket can help reduce acute fever.

Intravenous and oral fluids as well as certain medications are essential for maintaining kidney function during an acute episode.
Expectations (prognosis):
Episodes of the disorder can often be prevented. Repeated episodes or untreated episodes can cause kidney failure. Untreated episodes can be fatal. Fortunately, the use of the drug dantrolene has made fatalities much less common.
Complications:
  • Rhabdomyolysis, a kidney injury caused by excess myoglobin
  • Renal failure
  • Myopathy (weak muscles) or muscular dystrophy
  • Death
Calling your health care provider:
If you know that you or a member of your family has had problems with general anesthesia, or if you know you have a family history of malignant hyperthermia, be sure to notify both the surgeon and the anesthesiologist before having any surgery.
adam.com

©2012 About.com. The New York Times Company.