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Primary thrombocythemia

Overview Symptoms Treatment Prevention
Alternative Names:
Essential thrombocythemia; Essential thrombocytosis
Treatment:

If a patient is having life-threatening complications, rapid decrease of the platelet count may be achieved through platelet pheresis, a procedure to remove platelets from the blood directly.

Long-term decrease of the platelet count using medications can reduce both bleeding and clotting complications. Most common medications include hydroxyurea, interferon-alpha, or anagrelide. For patients with a known clotting tendency, aspirin may help decrease clotting episodes.

Some patients do not need any treatment.

Expectations (prognosis):
The outcome varies with reports ranging from prolonged periods without complications in some people, to fatalities from complications related to hemorrhage and thrombosis in others.
Complications:
  • Severe hemorrhage
  • Thrombotic episodes (stroke, heart attack, or blood clots in extremities)
  • Acute leukemia or myelofibrosis can develop in some patients
Calling your health care provider:
Blood cells
Blood cells
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